Title of article
Vanadium(III) chloride catalyzed Biginelli condensation: solution phase library generation of dihydropyrimidin-(2H)-ones
Author/Authors
Sabitha، نويسنده , , Gowravaram and Reddy، نويسنده , , G.S.Kiran Kumar and Reddy، نويسنده , , K.Bhaskar and Yadav، نويسنده , , J.S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
6497
To page
6499
Abstract
The three component condensation of an aldehyde, a β-keto ester and urea (thiourea) in the presence of a catalytic amount of VCl3 is disclosed for the solution phase synthesis of dihydropyrimidinones. The ease of synthesis and work-up allowed the parallel synthesis of a 48-membered library of dihydropyrimidinones quickly and efficiently in good yields.
Keywords
Parallel synthesis , Biginelli condensation , Dihydropyrimidin-2(1H)-ones , VCl3
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654110
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