Title of article
Chlorosulfonic acid as a convenient electrophilic olefin cyclization agent
Author/Authors
Linares-Palomino، نويسنده , , Pablo J and Salido، نويسنده , , Sof??a and Altarejos، نويسنده , , Joaqu??n and S?nchez، نويسنده , , Adolfo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
5
From page
6651
To page
6655
Abstract
Among several sulfonic acids studied (MeSO3H, p-TsOH, H2SO4, ClSO3H, FSO3H), the scarcely used chlorosulfonic acid showed to be an efficient agent for electrophilic olefin cyclizations with internal nucleophilic termination, in a similar manner that is well-established with fluorosulfonic acid. Its availability, lower price and relatively lesser handling problems makes ClSO3H an advantageous cyclizing agent particularly for high-scale applications. The stereochemical outcome of these cyclizations has been rationalized.
Keywords
Sulfonic acids , electrophilic olefin cyclization , odorants , Benzopyrans , Chlorosulfonic acid
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654227
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