Author/Authors :
Burguete، نويسنده , , M.Isabel and Collado، نويسنده , , Manuel and Escorihuela، نويسنده , , Jorge and Galindo، نويسنده , , Francisco and Garc??a-Verdugo، نويسنده , , Eduardo and Luis، نويسنده , , Santiago V and Vicent، نويسنده , , Mar??a J، نويسنده ,
Abstract :
Ni2+ complexes derived from simple α-amino amides catalyze very efficiently the addition of Et2Zn to benzaldehyde, giving (S)-1-phenylethanol as the major isomer in most cases (94% yield, 97% ee for R=Bn). The nature of the substituent on the amide nitrogen atom seems to play a key role in determining the asymmetric induction observed.
