Title of article
Nickel complexes from α-amino amides as efficient catalysts for the enantioselective Et2Zn addition to benzaldehyde
Author/Authors
Burguete، نويسنده , , M.Isabel and Collado، نويسنده , , Manuel and Escorihuela، نويسنده , , Jorge and Galindo، نويسنده , , Francisco and Garc??a-Verdugo، نويسنده , , Eduardo and Luis، نويسنده , , Santiago V and Vicent، نويسنده , , Mar??a J، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
6891
To page
6894
Abstract
Ni2+ complexes derived from simple α-amino amides catalyze very efficiently the addition of Et2Zn to benzaldehyde, giving (S)-1-phenylethanol as the major isomer in most cases (94% yield, 97% ee for R=Bn). The nature of the substituent on the amide nitrogen atom seems to play a key role in determining the asymmetric induction observed.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654416
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