Title of article :
6,7,14,15-Tetrahydro-15aH-azocino[1,2-a:6,5-b′]diindole. Synthesis of a novel pentacyclic ring system
Author/Authors :
Sripha، نويسنده , , Kittisak and Zlotos، نويسنده , , Darius P. and Buller، نويسنده , , Stefan and Mohr، نويسنده , , Klaus، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
In search of new lead structures for potent allosteric enhancers of antagonist binding to muscarinic M2 receptors, a novel heterocyclic ring system, 6,7,14,15-tetrahydro-15aH-azocino[1,2-a:6,5-b′]diindole, has been synthesized. The new ring skeleton was obtained from indol-2-yl-acetic acid in three steps.
Keywords :
6 , 7 , 14 , 2-a:6 , novel pentacyclic ring system , 5-b?]diindole , dimerization of 2-(indol-2-yl)-ethyl tosylate , intermolecular eight-ring formation via double alkylation , ligands for the allosteric binding site of muscarinic M2 receptors
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
