• Title of article

    Photochemical DNA cleavage by a Berenil analog

  • Author/Authors

    Burr، نويسنده , , Sally J. and Mselati، نويسنده , , Abdulghani and Thomas، نويسنده , , Emrys W.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    3
  • From page
    7307
  • To page
    7309
  • Abstract
    Berenil [bis(4-amidinophenyl)1,3-triazene] is a photostable DNA-binding ligand. We describe here the synthesis of N-(3-hydroxypropyl)-Berenil, which in contrast to Berenil is photosensitive to 360 nm irradiation, behaving as a caged diazonium salt. The 4-amidinobenzenediazonium fragment produced by photolysis induces DNA modification and cleavage.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1654739

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1654739