Title of article
Practical, efficient, stereoselective, formal synthesis of (2R,3R,4R)-3-hydroxy-4-methylproline
Author/Authors
Raghavan، نويسنده , , Sadagopan and Ramakrishna Reddy، نويسنده , , S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
7459
To page
7462
Abstract
A highly efficient and stereoselective synthesis of (2R,3R,4R)-HMP is disclosed employing the sulfinyl group as an internal nucleophile to functionalize an olefin in the key step of the reaction sequence. The proline ring is elaborated by a (4C+N) cyclization.
Keywords
Sulfoxide , bromohydrin , hydroxymethyl proline , stereoselective
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654835
Link To Document