Title of article :
Stereoselective synthesis of the α-glucosidase inhibitor nectrisine
Author/Authors :
Hulme، نويسنده , , Alison N. and Montgomery، نويسنده , , Charles H.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
The α-glucosidase inhibitor nectrisine was synthesised in 12 steps (31% overall yield) starting from d-serine. The three contiguous stereocentres of this iminosugar were introduced via a highly diastereoselective boron mediated glycolate aldol reaction.
Keywords :
Iminosugars , glycolate aldol , Glycosidase inhibitors
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
