Title of article
Product-like inhibitors of inositol monophosphatase
Author/Authors
M. Bashir-Uddin Surfraz، نويسنده , , M. and Miller، نويسنده , , David J. and Gani، نويسنده , , David and Allemann، نويسنده , , Rudolf K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
3
From page
7677
To page
7679
Abstract
A series of product-like inhibitors of inositol monophosphatase have been prepared and tested for activity in vitro as possible leads for treatment of bipolar disorders. Compounds possessing a 6-alkyloxy side chain were inhibitors but less efficacious than those possessing a 6-aminoalkyl side chain. These new structures show promise as inhibitors possessing the bioavailability and characteristics necessary for drug development.
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1654976
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