• Title of article

    Formal total synthesis of altohyrtin C (spongistatin 2). Part 1: Aldol approach to unite AB and CD spiroacetals

  • Author/Authors

    Terauchi، نويسنده , , Takeshi and Terauchi، نويسنده , , Taro and Sato، نويسنده , , Ippei and Shoji، نويسنده , , Wataru and Tsukada، نويسنده , , Tomoharu and Tsunoda، نويسنده , , Takashi and Kanoh، نويسنده , , Naoki and Nakata، نويسنده , , Masaya، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    5
  • From page
    7741
  • To page
    7745
  • Abstract
    The Mukaiyama aldol coupling of the second-generation C1C14 (AB) fragment of altohyrtins (spongistatins) with the model α-methyl-β-alkoxyaldehydes revealed that the stereochemistry at the newly formed carbon centers was controlled by the β-alkoxy chiral center of the model aldehydes. The union of the AB fragment with the C15C28 (CD) fragment under the same conditions gave the fully elaborated C1C28 (ABCD) subunit in good yield.
  • Keywords
    altohyrtins , spongistatins , stereoselective synthesis , aldol reaction
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1655024

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1655024