Author/Authors :
Rosas، نويسنده , , N and Sharma، نويسنده , , P and Alvarez، نويسنده , , C and Gَmez، نويسنده , , E and Gutiérrez، نويسنده , , Y and Méndez، نويسنده , , M and Toscano، نويسنده , , R.A and Maldonado، نويسنده , , L.A، نويسنده ,
Abstract :
The condensation of substituted α-keto alkynes with p-nitrobenzaldehyde in the presence of lithium diisopropylamide (LDA) affords highly substituted 5,6-dihydro-4H-oxocin-4-ones in good yields. Surprisingly, no six-membered carbocycles were formed in this 8-endo-dig cyclization to the oxocinone system.
