Author/Authors :
Li، نويسنده , , Bryan and Bemish، نويسنده , , Raymond and Buzon، نويسنده , , Richard A. and Chiu، نويسنده , , Charles K.-F. and Colgan، نويسنده , , Stephen T. and Kissel، نويسنده , , William and Le، نويسنده , , Tung and Leeman، نويسنده , , Kyle R. and Newell، نويسنده , , Lisa and Roth، نويسنده , , Joshua، نويسنده ,
Abstract :
Aqueous phosphoric acid (85 wt%) is an efficient and mild reagent for the deprotection of N-BOC groups. Acid sensitive functionalities including benzyl and methyl esters, TBDMS ether, CBZ and isopropylidene groups are compatible with the reaction conditions. The reactions are high yielding, and the workup is convenient.
