• Title of article

    Synthesis of β,β-branched β-amino ester derivatives through spiroaziridination of (α-trimethylsilanylmethyl)cyclohexylidene esters

  • Author/Authors

    Gasperi، نويسنده , , Tecla and Loreto، نويسنده , , M.Antonietta and Tardella، نويسنده , , P.Antonio، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    4
  • From page
    8467
  • To page
    8470
  • Abstract
    The reaction of (α-trimethylsilanylmethyl)cyclohexylidene esters with NsONHCO2Et and CaO produces the N-(ethoxycarbonyl)spiroaziridines which, after ring-opening, gives the corresponding β,β-disubstituted β-amino ester derivatives. The stereochemical outcome of the reaction is influenced by substituents on the cyclohexyl group.
  • Keywords
    allysilanes , ?-amino esters , Aziridines
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1655533