A novel chiral column for the HPLC separation of a series of dansyl amino and arylalkanoic acids

In a previous paper [C. Andre, M. Thomassin, A. Umrayami, L. Ismaili, B. Refouvelet, Y.C. Guillaume, Talanta 71 (2007) 1817] a novel cyclic hexapeptide molecule dissolved in the mobile phase was evaluated as a chiral selector (CS) for the enantiomer separation of a series of dansyl amino and arylalkanoic acids using high performance liquid chromatography (HPLC). In this paper, this CS was immobilized to the surface of a monolithic support and the enantioselectivity and the performance of this novel column are discussed.