Title of article
Short synthesis of a tetrasubstituted tetrahydropyran with five stereogenic centres—stereoselective double tandem rearrangements and cyclisation
Author/Authors
Greeves، نويسنده , , Nicholas and Lee، نويسنده , , Wai-Man and McLachlan، نويسنده , , Steven P and Oakes، نويسنده , , Graham H and Purdie، نويسنده , , Mark and Bickley، نويسنده , , Jamie F، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
9035
To page
9038
Abstract
A stereoselective potassium hydride/18-crown-6 mediated double tandem etherification-[2,3]-Wittig-anionic oxy-Cope rearrangement was used to prepare a δ,ε-unsaturated aldehyde with syn stereochemistry. Wittig olefination, dihydroxylation and stereoselective iodine induced cyclisation completed the tetrahydropyran skeleton.
Keywords
Iodoetherification , anionic oxy-Cope , 2 , 3]-Wittig , Ether , Sigmatropic
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1655900
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