Title of article
A novel reagent for the chemical phosphorylation of oligonucleotides
Author/Authors
Michael Leuck، نويسنده , , Michael and Vagle، نويسنده , , Kurt E and Shawn Roach، نويسنده , , J and Wolter، نويسنده , , Andreas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
321
To page
324
Abstract
A novel phosphoramidite reagent was developed to convert terminal hydroxyl groups of oligonucleotides into phosphate monoesters. The reagent’s appearance as a solid foam is advantageous for its manipulation and handling in solid-phase synthesis and improves its thermal stability.
Keywords
oligonucleotides , Chemical phosphorylation
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656369
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