Title of article
Allylstannation of N-acyliminium intermediates: a possible method for the stereocontrolled synthesis of polyhydroxypiperidines
Author/Authors
Chevallier، نويسنده , , Floris and Beaudet، نويسنده , , Isabelle and Le Grognec، نويسنده , , Erwan and Toupet، نويسنده , , Lo??c and Quintard، نويسنده , , Jean-Paul، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
761
To page
764
Abstract
The stereochemistry of the allylstannation of acyliminium intermediates has been examined for γ-alkoxyallyltins and γ-silyloxyallyltributyltins. In the latter case, the reaction has been shown to afford cleanly the syn adduct. Its subsequent ring-closing metathesis and dihydroxylation has allowed the highly stereoselective preparation of a 2-aryl-trihydroxypiperidine.
Keywords
Aminoalcohol derivatives , metathesis , Polyhydroxypiperidines , Allylstannation , iminium salts
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656664
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