Title of article :
Recent developments in the synthesis of 11β-aryl-estrone derivatives
Author/Authors :
Prat، نويسنده , , Denis and Benedetti، نويسنده , , Françoise and Nait Bouda، نويسنده , , Lahlou and Franc Girard، نويسنده , , Gilles، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
An industrial synthesis of 11β-aryl-estrone derivatives is described, based on the 1,4-addition of the aryl side-chain, as a cuprate, on to a mixture of allylic 5(10) alpha and beta epoxides, followed by hydrolysis and subsequent aromatization.
Keywords :
11-?-Aryl estrogen , aromatization , Industrial synthesis , Estrone derivatives
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
