Title of article
One-pot synthesis of α-diazo-β-hydroxyesters under phase-transfer catalysis and application to the catalytic asymmetric aldol reaction
Author/Authors
Arai، نويسنده , , Shigeru and Hasegawa، نويسنده , , Kazuya and Nishida، نويسنده , , Atsushi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
1023
To page
1026
Abstract
The one-pot (three steps) synthesis of α-diazo-β-hydroxyesters from tosyl chloride under phase-transfer catalysis is described. The catalytic asymmetric aldol reaction between a diazoester and aldehydes was also investigated and gave moderate to good enantioselectivity.
Keywords
aldol reaction , Ammonium salt , asymmetric synthesis , diazoester , phase transfer
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1656839
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