Efficient nucleophilic substitution reactions of highly functionalized allyl halides in ionic liquid media

Nucleophilic substitution reactions of highly functionalized allyl halides with three anions, N3−, AcO−, and PhSO2−, in ionic liquid media were conducted. The ionic liquid, [Bmim][BF4], was found to be superior to classical organic solvents to give higher yields and faster reaction rates. The resulting products belong to multifunctionalized trisubstituted α,β-unsaturated ketones, which are useful building blocks for organic synthesis.