Author/Authors :
Shintani، نويسنده , , Takuya and Kusabiraki، نويسنده , , Kazunori and Hattori، نويسنده , , Atsuko and Furutani، نويسنده , , Akinori and Tsutsumi، نويسنده , , Ken and Morimoto، نويسنده , , Tsumoru and Kakiuchi، نويسنده , , Kiyomi، نويسنده ,
Abstract :
The phenylmenthyl derivative, previously shown to be very effective chiral auxiliaries in the diastereoselective [2+2] photocycloaddition of cyclic enones with the simplest olefin, ethylene, was attached to poly(ethylene glycol)-grafted Wang resin. We then investigated the diastereoselective [2+2] photocycloaddition on solid support in several solvents. As the result, we accomplished good selectivity in toluene as well as the recycle of the polymer-supported chiral auxiliary. This is the first example that bicyclo[4.2.0]octane derivative has been obtained photochemically on the solid support.
Keywords :
(?)-8-Phenylmenthyl , chiral auxiliary , Polymer support , diastereoselectivity
