Studies on pyrrolidinones: a reaction of methylene dichloride under Friedel–Crafts conditions. Synthesis of an α-hydroxymethyl ketone in the hexahydrobenzo[f]indolizine series
Author/Authors :
Bourry، نويسنده , , Anne and Akué-Gédu، نويسنده , , Rufine and Hénichart، نويسنده , , Jean-Pierre and Sanz، نويسنده , , Gérard and Rigo، نويسنده , , Beno??t، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Pages :
5
From page :
2097
To page :
2101
Abstract :
When carried out in methylene dichloride, the Friedel–Crafts cyclization of N-arylmethyl pyroglutamates can lead to addition of a CH2OH group in the position α to the newly formed ketone function.