Stereocontrolled addition of boron enolates to trans α,β-aziridine aldehydes. A new route to anti-1,2-amino alcohols

A study of the addition of boron enolates of methyl ketones to trans α,β-aziridine aldehydes is reported. The reaction proceeds with excellent anti stereoselectivity furnishing functionalized products, capable of other controlled transformations, some of which are described.