Title of article
A facile synthesis of benzo[c]phenanthridine alkaloids: oxynitidine and oxysanguinarine using lithiated toluamide–benzonitrile cycloaddition
Author/Authors
Le، نويسنده , , Thanh Nguyen and Gang، نويسنده , , Seong Gyoung and Cho، نويسنده , , Won-Jea Cho، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
2763
To page
2766
Abstract
Benzo[c]phenanthridine alkaloids oxynitidine and oxysanguinarine were synthesized from easily available starting benzonitrile 5 and toluamide 6 using toluamide–benzonitrile cycloaddition reaction in six steps. This method is so highly efficient that it could be a more useful way for preparing fully aromatized benzo[c]phenanthridine compounds.
Keywords
nitidine , Sanguinarine , Synthesis of natural alkaloids
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1657769
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