Title of article
Suitable entry to a 10-membered ring with eleutheside functionality through Nozaki–Hiyama condensation
Author/Authors
Sandoval، نويسنده , , Celso and Redero، نويسنده , , Elena and Mateos-Timoneda، نويسنده , , Miguel A. and Bermejo، نويسنده , , Francisco A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
6521
To page
6524
Abstract
Access to a medium-sized unit of 15-seco-eleutheside analog 19 has been opened through the NiCl2/CrCl2-mediated intramolecular condensation of iodoaldehyde 8 with excellent yields. Transformation of the phenylcyclononanol 15 into the tetracyclic analog 19 was achieved in a four-step sequence with 65% overall yield.
Keywords
Anticancer agents , antimitotic , eleuthesides , sarcodictyns , eleutherobin , Nozaki–Hiyama condensation
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1657901
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