Title of article
Chemo-enzymatic synthesis of polyhydroxyazepanes
Author/Authors
Andreana، نويسنده , , Peter R. and Sanders، نويسنده , , Tom and Janczuk، نويسنده , , Adam and Warrick، نويسنده , , Joshua I. and Wang، نويسنده , , Peng George، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
6525
To page
6528
Abstract
Galactose oxidase (EC 1.1.3.9, GAO) is an extracellular copper-containing enzyme that utilizes molecular oxygen to convert the C6-primary hydroxyl moiety of d-galactopyranosides to hydrated aldehydes. Subsequent dehydratative coupling with hydroxylamines produces oximes (3a–f), which, when subjected to conditions of hydrogenolysis, give rise to polyhydroxyazepanes (11–17).
Keywords
aminosugar , chemo-enzymatic , Oxime , polyhydroxy , aldehyde , Galactose oxidase , Oxidation , Azepane
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1657907
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