Title of article
Construction of functionalised medium rings by stereospecific expansions of 2,3-epoxy alcohols under mild conditions
Author/Authors
Marson، نويسنده , , Charles M. and Khan، نويسنده , , Afzal and Porter، نويسنده , , Rod A. and Cobb، نويسنده , , Alexander J.A. Cobb، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
6637
To page
6640
Abstract
Ketones are converted with very high stereocontrol into functionalised medium rings incorporating a β-hydroxy ketone assembly via a ring-expansion mediated by tin(IV) chloride at low temperatures; either the threo or the erythro aldol products can be obtained. An asymmetric epoxidation permitted a subsequent highly enantiocontrolled semi-pinacol rearrangement.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658003
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