Title of article :
In-situ generation of Et3SiBr from BiBr3 and Et3SiH and its use in preparation of dialkyl ethers
Author/Authors :
Bajwa، نويسنده , , Joginder S. and Jiang، نويسنده , , Xinglong and Slade، نويسنده , , Joel and Prasad، نويسنده , , Kapa and Repic، نويسنده , , Oljan and Blacklock، نويسنده , , Thomas J.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
The reported BiBr3–Et3SiH catalyzed reductive etherifications of silyl ethers with carbonyl compounds are shown to be catalyzed by the in situ formed Et3SiBr and verified by an independent use of the commercial reagent. As Et3SiBr is moisture sensitive and is not readily available, this in situ generation is still recommended as the method of choice. Utilizing this method, several alcohols were transformed under very mild conditions into dialkyl ethers via their silyl intermediates, such as TES, TBDMS, and TIPS.
Keywords :
bismuth bromide , triethylsilane , triethylsilyl bromide , Silyl ethers , reductive etherification
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
