Title of article
Synthesis of enediyne model compounds possessing a cyanohydrin moiety as a triggering device
Author/Authors
Suzuki، نويسنده , , Ichiro and Tsuchiya، نويسنده , , Yuko and Shigenaga، نويسنده , , Akira and Nemoto، نويسنده , , Hisao and Shibuya، نويسنده , , Masayuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
6779
To page
6781
Abstract
Development of enediyne model compounds possessing a cyanohydrin moiety is described. These model compounds generate enyne–allenylketones efficiently under mild basic conditions and the resulting biradicals showed potent DNA cleaving abilities.
Keywords
radicals , Ionization , cyanohydrins , DNA , diynes , Enynes
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658094
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