Title of article
Tandem reaction of α-hypervalent iodo functionalized phosphonium and arsonium ylides as umpolung reagents
Author/Authors
Huang، نويسنده , , Zhi-Zhen and Yu، نويسنده , , Xiao-Chun and Huang، نويسنده , , Xian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
6823
To page
6825
Abstract
α-Hypervalent iodo functionalized phosphonium and arsonium ylides 2 can be used as umpolung ylides to react with nucleophiles to give α-heteroatom substituted ylides 4 in good yields. A tandem sequence of nucleophilic substitution then Wittig reaction occurs smoothly to form (Z)-α-halo-α,β-unsaturated esters 6, stereoselectively, in moderate to excellent yields.
Keywords
Tandem reaction , Synthesis , umpolung reagent , nucleophilic substitution , Wittig reaction
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658125
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