Title of article
Stereoselective formation of optically active 2-oxy-1,3-oxazolidin-4-ones and an efficient synthesis of optically active secondary 2-pyrrolidones
Author/Authors
Omata، نويسنده , , Yoji and Kakehi، نويسنده , , Akikazu and Shirai، نويسنده , , Masashi and Kamimura، نويسنده , , Akio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
6911
To page
6914
Abstract
Treatment of (−)-O-acyllactamides or mandelamides with TBSOTf in the presence of base gives optically active 2-oxy-1,3-oxazolidin-4-ones stereoselectively, which serve as useful precursors for the preparation of optically active secondary 2-pyrrolidones via radical cyclization and subsequent one-step removal of mandelic acid.
Keywords
chiral auxiliaries , acetals , ring constructions , radical cyclization , Heterocycles
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658165
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