Title of article
Non-cryogenic metalation of aryl bromides bearing proton donating groups: formation of a stable magnesio-intermediate
Author/Authors
Kato، نويسنده , , Shinji and Nonoyama، نويسنده , , Nobuaki and Tomimoto، نويسنده , , Koji and Mase، نويسنده , , Toshiaki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
7315
To page
7317
Abstract
Bromine–metal exchange of o-bromobenzoic acid (1) with Bu2Mg followed by n-BuLi was successfully carried out at non-cryogenic temperature (>−20°C), and gave a stabilized metal species which smoothly reacted with several electrophiles. This methodology expanded to several other bromides bearing proton donating groups (PDGs).
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658391
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