Title of article
An azetidinium ion approach to 3-aryloxy-3-aryl-1-propanamines
Author/Authors
OBrien، نويسنده , , Peter and Phillips، نويسنده , , David W. and Towers، نويسنده , , Timothy D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
7333
To page
7335
Abstract
Treatment of 3-(dimethylamino)-1-phenyl-propan-1-ol with mesyl chloride and then different phenols generates a range of N,N-dimethyl-3-aryloxy-3-aryl-1-propanamines via regiospecific opening of a proposed azetidinium ion intermediate. During the rearrangement process, there was some leakage of stereochemical integrity.
Keywords
neighbouring group effects , azetidinium ions , 3-aryloxy-3-aryl-1-propanamines , Phenols , amino alcohols
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658402
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