Title of article
Synthesis of protected syn 1,3-diols by intramolecular conjugate addition to vinyl sulfones
Author/Authors
Grimaud، نويسنده , , Laurence and Rotulo، نويسنده , , Delphine and Ros-Perez، نويسنده , , Rafael and Guitry-Azam، نويسنده , , Ludivine and Prunet، نويسنده , , Joëlle، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
7477
To page
7479
Abstract
A short route to sulfones 9a–c is described. These synthons encompassing a syn 1,3-diol motif are model compounds for the C16–C24 fragment of Dolabelides. The benzylidene protecting group can be reduced regioselectively to furnish β-hydroxysulfones 10a–b. First attempts of Julia coupling of the dianions derived from these substrates with aldehydes and ketones are also reported.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1658485
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