• Title of article

    Synthesis of constrained cycloalkyl analogues of glutamic acid with an ω-phosphonic acid function

  • Author/Authors

    Bessières، نويسنده , , Bernard and Schoenfelder، نويسنده , , Angèle and Verrat، نويسنده , , Céline and Mann، نويسنده , , André and Ornstein، نويسنده , , Paul and Pedregal، نويسنده , , Conception، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    7659
  • To page
    7662
  • Abstract
    A general method based on the sequential reactivities of bis-bromocycloalkenes (3–5) is proposed for the preparation of phosphonocycloalkanes (1a/b–3a/b), representing structural constrained analogues of AP4. For the synthesis of an additional congested AP4 analogue (4), an intramolecular cyclopropanation of a ketocarbene towards a vinyphoshonate, assisted by Rh(OAc)2 was successfully experimented.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1658599