• Title of article

    Ozonization and reduction of α-methylene N-(ethoxycarbonyl)-β-amino phosphonic esters

  • Author/Authors

    Francavilla، نويسنده , , Matteo and Gasperi، نويسنده , , Tecla and Loreto، نويسنده , , M.Antonietta and Tardella، نويسنده , , Paolo A. and Bassetti، نويسنده , , Mauro، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    7913
  • To page
    7916
  • Abstract
    N-(Ethoxycarbonyl)-β-amino-α-methylene phosphonic esters give N-(ethoxycarbonyl)-β-amino-α-hydroxy phosphonic esters by ozonization and subsequent reduction with a large excess of NaBH4. If there is a small excess of NaBH4 or if the intermediate is treated with methanolic NaOH–CH2Cl2 an anomalous ozonolysis occurs, affording N-(ethoxycarbonyl)-α-amino methyl carboxylic esters due to the cleavage of both the CC double bond and the adjacent CP single bond.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1658760

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1658760