Author/Authors :
Hammarstrِm، نويسنده , , Lars G.J and Smith، نويسنده , , David B. and Talamلs، نويسنده , , Francisco X and Labadie، نويسنده , , Sharada S and Krauss، نويسنده , , Nancy E، نويسنده ,
Abstract :
4,6-Dichloro-2-(methylthio)-5-nitropyrimidine has been utilized as a building block for an efficient nine-step synthesis of olomoucine. The methodology reported herein is applicable to the regiocontrolled solution and solid-phase synthesis of libraries of highly substituted purines, as well as other related scaffolds.
