Title of article :
Nitrooxyquinones: synthesis, X-ray diffraction and electrochemical studies
Author/Authors :
de Abreu، نويسنده , , Fabiane C. and de O. Lopes، نويسنده , , Adriana and Pereira، نويسنده , , Mariano Alves and De Simone، نويسنده , , Carlos Alberto and Goulart، نويسنده , , Marilia O.F. Goulart، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
2-Methyl-3-(nitrooxymethyl)-[1,4]-naphthoquinone and 2-(nitrooxymethyl)-[9,10]-anthraquinone, the first representatives of quinone-derived organic nitrates, potential hybrid drugs, were obtained and characterized through X-ray diffraction. Voltammetric studies showed that reductive elimination occurs, after quinone reduction. The NO3− release, leading to electrogenerated quinonemethide, would suggest a quinone-driven biological activity.
Keywords :
quinones , Organic nitrates , Redox potential , Cyclic voltammetry , electrolysis , reductive elimination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
