Author/Authors :
de Koning، نويسنده , , Martijn C. and Filippov، نويسنده , , Dmitri V and Meeuwenoord، نويسنده , , Nico and Overhand، نويسنده , , Mark and van der Marel، نويسنده , , Gijs A. and van Boom، نويسنده , , Jacques H، نويسنده ,
Abstract :
A convenient solid-phase synthesis of a PNA sequence containing an N-terminal thiaproline and a C-terminal thioester is described. The usefulness of this bifunctional PNA molecule is illustrated by the construction, based on native ligation, of a peptide–PNA–peptide adduct.