• Title of article

    Synthesis of [18-C-6]-β3-(L)-DOPA, first β-amino acid with a crown-ether receptor side-chain

  • Author/Authors

    Gaucher، نويسنده , , Anne and Barbeau، نويسنده , , Olivier and Hamchaoui، نويسنده , , Wahib and Vandromme، نويسنده , , Lucie and Wright، نويسنده , , Karen and Wakselman، نويسنده , , Michel and Mazaleyrat، نويسنده , , Jean-Paul، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    8241
  • To page
    8244
  • Abstract
    Terminally protected Boc-β3-(L)-DOPA-OMe has been synthesized from (L)-DOPA by the Arndt–Eistert homologation procedure. Then, a first crown-ether derivative, Boc-[18-C-6]-β3-(L)-DOPA-OMe, has been obtained by bis-O-alkylation of the catechol function with cyclization, using Cs2CO3 as base and pentaethyleneglycol ditosylate as alkylating agent, in DMF at 60°C.
  • Keywords
    ?-Amino acids , ?-Peptides , ?3-(L)-DOPA , Crown-ethers
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1658955

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1658955