Title of article
Enzymatic resolution of diethyl (3-hydroxy-1-butenyl) phosphonate
Author/Authors
Attolini، نويسنده , , Mireille and Iacazio، نويسنده , , Gilles and Peiffer، نويسنده , , Gilbert and Maffei، نويسنده , , Michel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
8547
To page
8549
Abstract
The enzymatic esterification of diethyl (3-hydroxy-1-butenyl) phosphonate 1 with different enzymes has been carried out, and allows the preparation of (S)-1 and (R)-diethyl (3-acetoxy-1-butenyl) phosphonate 2 with very high enantiomeric excess. The absolute conguration of 1 was determined by independent synthesis from (S)-ethyl lactate.
Keywords
Enzymatic esterification , diethyl (3-hydroxy-1-butenyl) phosphonate , resolution of organophosphorus compounds
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659141
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