Title of article
Pyrrolidinic and piperidinic ring fission by conjugate elimination
Author/Authors
Acquadro، نويسنده , , Francesco and Oulyadi، نويسنده , , Hassan and Venturello، نويسنده , , Paolo and Maddaluno، نويسنده , , Jacques، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
8759
To page
8763
Abstract
Treating N-substituted pyrrolidines and piperidines bearing an allylic chain α to the nitrogen with strong bases leads to the opening of the heterocycle and provides 1,3-dienes disubstituted with an alkoxy and an aminoalkyl chain. The effects of the base and the solvent have been studied, as well as the influence of the ring size and the nitrogen substituent. The results obtained suggest a possible pre-chelation of the base cation before the deprotonation.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659255
Link To Document