Title of article
Efficient synthesis of substituted 2-aminopyrazines: FeCl3-promoted condensation of hydroxyiminoketones with aminoacetonitriles
Author/Authors
Itoh، نويسنده , , Takahiro and Maeda، نويسنده , , Kenji Isoe-Wada، نويسنده , , Toshihiro and Tomimoto، نويسنده , , Koji and Mase، نويسنده , , Toshiaki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
9287
To page
9290
Abstract
FeCl3-promoted condensation of hydroxyiminoketones with aminoacetonitriles followed by catalytic hydrogenation afforded the desired pyrazines in moderate–good yields. This protocol provides an efficient and practical synthesis of substituted 2-aminopyrazines.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659563
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