Author/Authors :
Le Gal، نويسنده , , Julien and Benoist، نويسنده , , Eric and Gressier، نويسنده , , Marie and Coulais، نويسنده , , Yvon and Dartiguenave، نويسنده , , Michèle، نويسنده ,
Abstract :
The synthesis of two new N2S2 or N2SO tetradentate ligands and the preparation of their technetium-99m complexes are reported. Each ligand leads to a unique 99mTc-complex with an excellent radiochemical yield. The in vivo stability of these complexes was determined by serum stability and cysteine challenge studies.