Title of article
Three-component one-pot synthesis of functionalised (Z)-4-benzylidene (and alkenylidene) pyrrolidines
Author/Authors
Azoulay، نويسنده , , Stéphane and Monteiro، نويسنده , , Nuno and Balme، نويسنده , , Geneviève، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
9311
To page
9314
Abstract
A three-component synthesis of stereodefined 4-benzylidene-(or alkenylidene)-pyrrolidines from simple, readily available starting materials is described. This one-pot process is initiated by a conjugate addition of a propargylamine to a gem-diactivated olefin subsequently followed by a carbopalladation involving an aryl halide (or vinyl triflate).
Keywords
multicomponent reactions , carbocyclisation , Pyrrolidines , Palladium catalysis
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1659578
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