Title of article :
Synthesis of the acyl side chain segment of polyoxypeptins using regioselective ring-opening of chiral 2,3-epoxy alcohol
Author/Authors :
Makino، نويسنده , , Kazuishi and Suzuki، نويسنده , , Tatsuya and Awane، نويسنده , , Shinobu and Hara، نويسنده , , Osamu and Hamada، نويسنده , , Yasumasa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
The acyl side chain segment 2 contained in polyoxypeptins A (1a) and B (1b), apoptosis-inducing cyclodepsipeptides, was synthesized from chiral 2,3-epoxy alcohol (6), easily prepared by Sharpless asymmetric epoxidation, through a regioselective ring-opening reaction as the key step.
Keywords :
polyoxypeptins , cyclodepsipeptide , regioselective ring-opening , 2 , 3-epoxy alcohol
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
