• Title of article

    A chiral tricyclic proline analogue obtained from camphor

  • Author/Authors

    Marian V. Gorichko، نويسنده , , Marian V and Grygorenko، نويسنده , , Oleksandr O and Komarov، نويسنده , , Igor V، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    2
  • From page
    9411
  • To page
    9412
  • Abstract
    Synthesis of 3a,6a-dimethylhexahydro-1,4-methanocyclopenta[c]pyrrole-1(2H)-carboxylic acid, a new chiral constrained proline analogue is reported. The synthesis was accomplished in five steps from 8-bromocamphor, easily available in both enantiomeric forms. A key step in the synthesis is an intramolecular ‘domino’-type cyclisation, initiated by a nucleophile attack at an activated CN bond.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1659633

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1659633