Title of article
Installation of carbon chain onto 2-cyclohexene-1,4-diol monoacetate
Author/Authors
Abbas، نويسنده , , Ashraf A. and Kobayashi، نويسنده , , Yuichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
119
To page
122
Abstract
Alkylation of cyclohexenyl monoacetate 1 with R2Cu(CN)(MgCl)2 or RMgBr/CuCN (cat.) in Et2O produced trans 1,2-isomers 4, while arylation and alkenylation of 1 was accomplished with lithium borates 5 and a nickel cat. to afford trans 1,4-isomers 3 selectively. Furthermore, several transformations of the products were carried out to demonstrate synthetic advantages of the present reactions.
Keywords
Grignard reagent , copper catalyst , Lithium borates , Nickel catalyst , Coupling reaction , 4-diol monoacetate , cyclohexene-1
Journal title
Tetrahedron Letters
Serial Year
2003
Journal title
Tetrahedron Letters
Record number
1659886
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