Author/Authors :
Mourtas، نويسنده , , Spyros and Katakalou، نويسنده , , Christina and Nicolettou، نويسنده , , Andriana and Tzavara، نويسنده , , Chryssoula and Gatos، نويسنده , , Dimitrios and Barlos، نويسنده , , Kleomenis، نويسنده ,
Abstract :
Aminothiols were attached through their thiol group onto the 4,4′-dimethoxytrityl (Dmt)-, 4-methoxytrityl (Mmt)-, 4-methyltrityl (Mtt)-, trityl (Trt)- and 2-chlorotrityl (Clt)-resins. The new resins were used in the solid-phase synthesis of aminothiol containing peptides utilizing N-Fmoc amino acids. The synthesized peptides were cleaved from the resins by treatment with trifluoroacetic acid (TFA) solutions using triethylsilane (TES) or ethanedithiol (EDT) as scavengers.
