• Title of article

    [6-13C]-(2S,4S)-5-Chloroleucine: synthesis and incubation studies with cultures of the cyanobacterium, Lyngbya majuscula

  • Author/Authors

    Gerwick، نويسنده , , William H. and Leslie، نويسنده , , Pauline and Long، نويسنده , , G.Cliona and Marquez، نويسنده , , Brian L. and Willis، نويسنده , , Christine L.، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    4
  • From page
    285
  • To page
    288
  • Abstract
    [6-13C]-(2S,4S)-5-Chloroleucine 12 was prepared in six steps and 26% overall yield from protected l-glutamic acid using 13CH3I as the source of isotopic label. On feeding 12 to cultures of L. majuscula no incorporation of isotopic label into the trichlorinated marine natural product barbamide was detected. The synthesis of a novel dichloroleucine derivative 16 is also described.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1659981