Author/Authors :
Takahashi، نويسنده , , Kyoko and Hashimoto، نويسنده , , Kenichiro and Fujiyama، نويسنده , , Ayako and Yamada، نويسنده , , Junko and Kobayashi، نويسنده , , Noriko and Morisaki، نويسنده , , Masuo and Nakano، نويسنده , , Sayaka and Hara، نويسنده , , Noriyuki and Fujimoto، نويسنده , , Yoshinori، نويسنده ,
Abstract :
Feeding of the chemically prepared [24-13C, 24-2H]desmosterol to cell-free systems derived from rat liver and silkworm gut and to cultured cells of Oryza sativa followed by deuterium-decoupled 1H, 13C shift correlation NMR analysis of the biosynthesized cholesterol revealed the stereospecific incorporation of hydrogen atoms from the re-face of the C-24 position of desmosterol.
Keywords :
Stereochemistry , 3?-hydroxysterol ?24-reductase , steroids and sterols , Cholesterol biosynthesis , Desmosterol
